Field Intelligence
A strategy is only as strong as the information behind it. PSI gathers field insights, synthesizes academic and institutional data, and turns this knowledge into practical resources for those who need it most.
Field Intelligence
A strategy is only as strong as the information behind it. PSI gathers field insights, synthesizes academic and institutional data, and turns this knowledge into practical resources for those who need it most.
Disclaimer
Disclaimer
Disclaimer
PSI does not endorse, encourage, or facilitate the use of illicit substances. All our information is for educational purposes only and should not replace consultation with qualified healthcare providers.
Our content is based on publicly available information, non-representative surveys, and stakeholder interviews, with inherent limitations in scope and representation. Data analysis involved AI assistance and is subject to human error and interpretation variability. Individual psychedelic experiences vary greatly and may not be fully represented in our resources.
Users should be aware that some content may be triggering, particularly materials addressing harm and misconduct. We acknowledge that our resources provide a partial view of the rapidly evolving psychedelic ecosystem and welcome community feedback for improvements.
For a full list of disclaimers and limitations, click here.
PSI does not endorse, encourage, or facilitate the use of illicit substances. All our information is for educational purposes only and should not replace consultation with qualified healthcare providers.
Our content is based on publicly available information, non-representative surveys, and stakeholder interviews, with inherent limitations in scope and representation. Data analysis involved AI assistance and is subject to human error and interpretation variability. Individual psychedelic experiences vary greatly and may not be fully represented in our resources.
Users should be aware that some content may be triggering, particularly materials addressing harm and misconduct. We acknowledge that our resources provide a partial view of the rapidly evolving psychedelic ecosystem and welcome community feedback for improvements.
For a full list of disclaimers and limitations, click here.
Use and Attribution
Use and Attribution
Use and Attribution
For guidelines on referencing, sharing, using, and building upon the materials developed by the Psychedelic Safety Institute (PSI), click here.
For guidelines on referencing, sharing, using, and building upon the materials developed by the Psychedelic Safety Institute (PSI), click here.
Knowledge Base
Knowledge Base
Knowledge Base
PSI has developed a knowledge base of information related to psychedelic psychedelic safety, harm reduction, and public health. A field can only align if it has shared knowledge and language. PSI synthesizes insights from peer-reviewed research, clinical trials, case reports, government datasets, harm reduction field reports, and practitioner guidance — making the best available evidence accessible and actionable across the psychedelic ecosystem.
Literature
Review
Summary of the state of academic knowledge on nine psychedelic substances’ risks & mitigations.
Explore
Epidemiological Profile Summary
Global patterns of psychedelic use and public health implications.
Explore
Risk and Harm
Typology
A framework to identify and understand psychedelic-related risks and harms.
A framework to identify and understand psychedelic-related risks and harms.
Explore
Misconduct Typology
A framework to identify and understand types of practitioner misconduct to support ethical behavior.
A framework to identify and understand types of practitioner misconduct to support ethical behavior.
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Case Book
37 documented real-world incidents highlighting safety challenges and lessons learned.
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The Ethics Toolkit
A practical framework for ethical risks management for practitioners.
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Field Research
Field Research
PSI has conducted systematic field research across legal, therapeutic, underground, and campus contexts to understand real-world needs, challenges, and safety priorities in the psychedelic space. This collection represents a comprehensive effort to map the psychedelic landscape through direct engagement with stakeholders across legal, therapeutic, underground, and campus contexts.
These resources document what we learned by going directly to the field — not just published literature, but lived experience from those working at the frontlines of psychedelic access, harm reduction, and policy reform. We share these resources publicly to benefit the entire field and support evidence-based advocacy, harm reduction programming, policy development, and further research.
Explore the Research
Evidence-Based Guidance
for Safer Psychedelic Experiences
Psychedelic use is happening across diverse contexts — from clinical trials and regulated frameworks to underground ceremonies and personal exploration. To support safety across this spectrum, we've developed comprehensive educational guides that synthesize research, case reports, and field expertise into practical, evidence-based resources.
Each guide is designed for a specific audience but shares a common foundation: preparing thoughtfully, recognizing risks early, responding compassionately, and supporting meaningful integration.
Educational Guides
Disclaimer
PSI does not endorse, encourage, or facilitate the use of illicit substances. All our information is for educational purposes only and should not replace consultation with qualified healthcare providers. Our content is based on publicly available information, non-representative surveys, and stakeholder interviews, with inherent limitations in scope and representation. Data analysis involved AI assistance and is subject to human error and interpretation variability. Individual psychedelic experiences vary greatly and may not be fully represented in our resources. Users should be aware that some content may be triggering, particularly materials addressing harm and misconduct. We acknowledge that our resources provide a partial view of the rapidly evolving psychedelic ecosystem and welcome community feedback for improvements. For a full list of disclaimers and limitations, click here.
Use and Attribution
For guidelines on referencing, sharing, using, and building upon the materials developed by the Psychedelic Safety Institute (PSI), click here.
Disclaimer
PSI does not endorse, encourage, or facilitate the use of illicit substances. All our information is for educational purposes only and should not replace consultation with qualified healthcare providers. Our content is based on publicly available information, non-representative surveys, and stakeholder interviews, with inherent limitations in scope and representation. Data analysis involved AI assistance and is subject to human error and interpretation variability. Individual psychedelic experiences vary greatly and may not be fully represented in our resources. Users should be aware that some content may be triggering, particularly materials addressing harm and misconduct. We acknowledge that our resources provide a partial view of the rapidly evolving psychedelic ecosystem and welcome community feedback for improvements. For a full list of disclaimers and limitations, click here.
Use and Attribution
For guidelines on referencing, sharing, using, and building upon the materials developed by the Psychedelic Safety Institute (PSI), click here.
Disclaimer
PSI does not endorse, encourage, or facilitate the use of illicit substances. All our information is for educational purposes only and should not replace consultation with qualified healthcare providers. Our content is based on publicly available information, non-representative surveys, and stakeholder interviews, with inherent limitations in scope and representation. Data analysis involved AI assistance and is subject to human error and interpretation variability. Individual psychedelic experiences vary greatly and may not be fully represented in our resources. Users should be aware that some content may be triggering, particularly materials addressing harm and misconduct. We acknowledge that our resources provide a partial view of the rapidly evolving psychedelic ecosystem and welcome community feedback for improvements. For a full list of disclaimers and limitations, click here.
Use and Attribution
For guidelines on referencing, sharing, using, and building upon the materials developed by the Psychedelic Safety Institute (PSI), click here.
Disclaimer
PSI does not endorse, encourage, or facilitate the use of illicit substances. All our information is for educational purposes only and should not replace consultation with qualified healthcare providers. Our content is based on publicly available information, non-representative surveys, and stakeholder interviews, with inherent limitations in scope and representation. Data analysis involved AI assistance and is subject to human error and interpretation variability. Individual psychedelic experiences vary greatly and may not be fully represented in our resources. Users should be aware that some content may be triggering, particularly materials addressing harm and misconduct. We acknowledge that our resources provide a partial view of the rapidly evolving psychedelic ecosystem and welcome community feedback for improvements. For a full list of disclaimers and limitations, click here.
Use and Attribution
For guidelines on referencing, sharing, using, and building upon the materials developed by the Psychedelic Safety Institute (PSI), click here.
Let’s build the future together
Your ideas and experiences drive this field forward. Share your thoughts, ask a question, or suggest a collaboration — we’re always open to new connections.
Or reach us directly
hello@psychedelicsafety.institute
Let’s build the future together
Your ideas and experiences drive this field forward. Share your thoughts, ask a question, or suggest a collaboration — we’re always open to new connections.
Or reach us directly
hello@psychedelicsafety.institute
Let’s build the future together
Your ideas and experiences drive this field forward. Share your thoughts, ask a question, or suggest a collaboration — we’re always open to new connections.
Or reach us directly
hello@psychedelicsafety.institute
Let’s build the future together
Your ideas and experiences drive this field forward. Share your thoughts, ask a question, or suggest a collaboration — we’re always open to new connections.
Or reach us directly
hello@psychedelicsafety.institute
Stay Connected
Join our community of researchers, practitioners, policymakers, advocates, and harm reductionists working to align the psychedelic field around safety and public interest.
© 2025 Psychedelic Safety Institute. All rights reserved
Stay Connected
Join our community of researchers, practitioners, policymakers, advocates, and harm reductionists working to align the psychedelic field around safety and public interest.
© 2025 Psychedelic Safety Institute. All rights reserved
Stay Connected
Join our community of researchers, practitioners, policymakers, advocates, and harm reductionists working to align the psychedelic field around safety and public interest.
© 2025 Psychedelic Safety Institute. All rights reserved
Stay Connected
Join our community of researchers, practitioners, policymakers, advocates, and harm reductionists working to align the psychedelic field around safety and public interest.
© 2025 Psychedelic Safety Institute. All rights reserved